A brief reading of the sentences suggests that the paragraph is about the change needed in the way we go about development. 2 introduces the topic at hand, that this is a watershed moment when it comes to the subject of development. 41 make a mandatory pair, which talks about what the purpose of development was at the beginning and how it needs to be altered to suit the needs of today. 3 then aptly ends the paragraph, suggesting the measures that could be taken to counter the same. Hence, he proper sequence would be 2413.applications.