Concept:Recognize 4x2+16y2−16xy as (2x−4y)2. Let k=2x−4y to simplify the expression into a quadratic in k, then factorize.Explanation:First, rewrite the middle term: 4x2+16y2−16xy=(2x)2+(4y)2−2(2x)(4y)=(2x−4y)2.The expression becomes 5(2x−4y)+6(2x−4y)2−6.Let k=2x−4y. Then the expression is 6k2+5k−6.Factor this quadratic: look for two numbers whose product is 6×(−6)=−36 and sum is 5. These are 9 and −4.So 6k2+5k−6=6k2+9k−4k−6=3k(2k+3)−2(2k+3)=(3k−2)(2k+3).Substitute k back: 3k−2=3(2x−4y)−2=6x−12y−2=2(3x−6y−1).Hence one factor is 3x−6y−1. The other factor 2k+3=2(2x−4y)+3=4x−8y+3 does not match the options.Thus, the correct factor among the choices is 3x−6y−1.Answer:3x−6y−1 (Option C)