Concept:Simplify the expression using the law of exponents: anam=am−n.Explanation:The given expression is 212×36×53216×310×54.Subtract exponents for each base in the numerator and denominator:216−12=24=16,310−6=34=81,54−3=51=5.Multiply the results: 16×81×5=16×5×81=80×81=6480.Answer:6480, which is option B.