Concept:Renin-Angiotensin mechanism is a hormonal cascade that regulates blood pressure and GFR.
Key Fact:The sequence starts with a fall in GFR, which triggers renin release.
Explanation:A fall in GFR (C) activates the JG cells to release renin.
Renin converts angiotensinogen to angiotensin I, then angiotensin II (E).
Angiotensin II causes vasoconstriction and stimulates aldosterone release (D).
Aldosterone promotes reabsorption of
Na+ and water from distal tubule (B).
This increases blood pressure and GFR (A).
Answer:Correct order: C, E, D, B, A. Option D matches.