Concept:Use repeated difference of squares: (a−b)(a+b)=a2−b2.Explanation:Let P=(2+1)(22+1)(24+1)(28+1)(216+1).Since 2−1=1, multiplying by (2−1) does not change P.So P=(2−1)(2+1)(22+1)(24+1)(28+1)(216+1).Now apply the identity repeatedly:(2−1)(2+1)=22−1.(22−1)(22+1)=24−1.(24−1)(24+1)=28−1.(28−1)(28+1)=216−1.(216−1)(216+1)=232−1.Thus P=232−1.Required value =232−(232−1)=1.Answer:1, so the correct option is B.