We have, 1+16x2y=tan(x−2y) On differentiating w.r.t. x, we get 32xy+16x2dxdy=sec2(x−2y)(1−2dxdy)⇒dxdy(16x2+2sec2(x−2y)=sec2(x−2y)−32xy⇒dxdy=16x2+2sec2(x−2y)sec2(x−2y)−32xy Slope of tangent at (4π,0) i.e. (dxdy)(4π,0)=16×(4π)2+2sec2(4π−0)sec2(4π−0)−32(4π)(0)∴ Slope of tangent =π2+42