Hint −> See the hydrogen bounded structure of A−T (Adenine - Thymine) and - G-C(Guanine- Cytosine) Solution : ⇒ No OH bond between A−T=2 Average energy of each H bond in A−T pair =X Kcal mol−1 Total no of A−T pair in structure =5 Hence, total energy =2x×5=10x → No of H bond between G−C=3 Average energy of each H-bond in G-C pair = Y Kcal mol−1 Total no of G−C pair in structure =3 Hence total energy =3y×3=9y -> Now, the total energy required to split all double-stranded DNA into two single strands. =10x+9y