The given series is an alternate series of numbers and letters.
B, 2, Y, 3, V, ?, S, 7, ?, 11, M
The pattern followed by the numbers is:-
The numbers are all prime numbers.
Prime numbers:- 2, 3, 5, 7, 11
So, the first '?' is '5'.
The pattern followed by letters is:-
The difference between the consecutive letters' positional values is 3.
So, the second '?' is 'P'.
Hence, the correct answer is "5, P".