The correct answer is the RBC will shrink. Key Points - Isotonic Solution: The concentration of solute remains the same both inside and outside the cell. - Hypotonic Solution: A hypotonic solution has a lower concentration of solutes than another solution. - Hypertonic Solution: A solution that has a higher concentration of solutes such as salt, than is found in normal cells and blood. - The water diffuses from a region of higher concentration to a region of lower concentration. - Salt in RBC=0.9% and salt in detergent =2%, thus it is hypertonic solution. - In this case, RBC is placed in a hypertonic solution and having more water, while detergent having less concentration of water. - Thus, due to osmosis, water from the RBC would diffuse to detergent solution and the RBCs will shrink.